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For the first time ever, it showcases complete automation of SFE sample pre-treatment and analysis by liquid or supercritical fluid chromatography. The Nexera UC system is designed to fulfil the measurement requirements of a wide range of applications including: monitoring of pesticides in food products; investigation of biomarkers; additives in polymers; drug discovery in pharmaceuticals and biopharmaceuticals, environmental controls and cleaning validation, to name just a few.
Increasing speed and efficiency while reducing the risk of human error in the analytical workflow The Nexera UC online SFE-SFC approach eliminates the need for tedious, manual sample pretreatment. All samples are extracted under light-shielding, anaerobic conditions, enabling highly reproducible analysis even of unstable compounds that are easily oxidized or degraded using a conventional liquid extraction method.
Furthermore, the fully automated Nexera UC system offers much higher recovery rates of target analytes while significantly reducing the risk of human error during sample pretreatment. Nexera UC system highlights 1.
Industry-leading sample throughput for supercritical fluid extraction, enabling up to 48 samples to be continuously and automatically processed 3. Achieves the highest levels of sensitivity due to split-less injection of the entire volume of eluent into the mass spectrometer Technological background The innovative Nexera UC system offers a supplementary chromatographic technique to conventional LC and GC analysis that enables separation of an even wider range of non- to very polar analytes.
Automated extraction and chromatography is achieved using a mobile phase of supercritical carbon dioxide which exhibits the solubility of a liquid with the diffusivity of a gas. Solvent strength can be increased by adding pre? ul de dating swiss polar co-solvent.
SFE and SFC are therefore faster, more efficient, cheaper and more environmentally friendly than other methods using large amounts of toxic organic solvents. The Nexera UC serves a wide range of applications, e.
It enables highly reproducible extraction and stable analysis even of unstable samples prone to oxidation or dissociation if exposed to light or air.